Teratogenic action of adenine on mouse embryos.

TERATOGENIC EFFECTS OF LITHIUM CARBONATE ON DEVELOPMENT OF MOUSE EMBRYOS

اثرات تراتوژنیک ویتامین A بر شکل‌گیری لوله عصبی در جنین موش

ABSTRACT In this study we have tried to analyse the effect of vit.A ampule(retinol )on formation of neural tube (neurulation)in mouse (balb/c)embryo to determine the critical time of its formation and the optimum teratogenic dose of this substance in the experimental induction of neral tube defects(NTD). After we observed the vaginal plug(v.p=0day),mated animals were divided into two groups ...

In Vivo Study of Diethylstilbestrol Teratogenicity on Mouse Embryo

        Diethylstilbestrol (DES) was widely used in the past, as the morning after contraception, but its application became extremely limited due to several complications including delayed clear cell adenocarcinoma in female infants. However, the use of DES increased during the past decade for hormone replacement therapy. The aim of this study was to investigate possible teratogenicity of this...

CIGARETTE SMOKE/ETHANOL-INDUCED LIMB DEFECTS IN MOUSE EMBRYOS

We have produced a spectrum of limb defects in developing mouse embryos by exposing the mother to smoke from cigarettes with different nicotine concentrations, ethanol, and a combination of ethanol and cigarette smoke. The critical time of exposure was determined to be during day 10 of gestation (vaginal plug=day 0). This time is prior to the critical events which occur between the apical e...

Investigation on the teratogenic and embryotoxic effects of nanozeolite on chick embryos model

Objective(s): In veterinary medicine, zeolites are used as toxin binder in animal feed, ammonia purification of aquatic pools, animal smell and moisture control. This study investigated on the risk assessment of nano zeolite on development of embryonic chicken models, anomalies, tetratogenic and embryotoxic effects. Methods: Eggs (120 = n) were accidentally di...